Persistent Heartburn

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Heartburn and Ulcer Drug Pepcid Now Available as Generic
FDA Consumer magazine, - July-August 2001
The prescription drug Pepcid (famotidine), used for the short-term treatment of heartburn and peptic ulcers, is now available in generic form. The FDA approved more than two dozen companies' generic versions in April and May, following the end of Pepcid's patent protection, held by Merck Laboratories, on April 15.

Famotidine is available as a tablet and an injection. The drug treats heartburn and non-cancerous ulcers of the digestive system by reducing the amount of stomach acid produced. Felt as a burning sensation in the chest, heartburn is caused by stomach acid eating away at the esophagus.

Heartburn is not life-threatening, but it may be a sign of a more serious problem, such as gastroesophageal reflux disease (GERD). GERD occurs when the muscle valve at the lower end of the esophagus malfunctions, allowing stomach acid to flow up into the esophagus. Left untreated, GERD can cause complications such as Barrett's esophagus (a pre-cancerous condition of the esophagus).

An estimated 15 million Americans experience heartburn every day, according to the American College of Gastroenterology.

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